Medical Term: Ia Like Antigens, Human | Human Ia Like Antigens defined

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What is Ia Like Antigens, Human | Human Ia Like Antigens?


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Term Definition: Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.


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