Medical Term: IkB defined

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What is IkB?

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Term Definition: Family of inhibitory proteins which bind to the rel family of transcription factors and modulate their activity. The transcription factor NF-KAPPA B is generally present in an inactive cytoplasmic form, bound to inhibitory IkB proteins. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

 

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