Medical Term: N Acetylgalactosamine 4 sulphate Sulphatase defined

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What is N Acetylgalactosamine 4 sulphate Sulphatase?

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Term Definition: An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.

 

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